gcm2/Gcm2/GCMB

Drosophila melanogaster glial cells missing 2 (gcm2) and its murine ortholog Gcm2 are required for plasmatocytes‘ conversion into macrophages and parathyroid gland development, respectively. So I wish to raise the following question:

Can we induce endoderm-mesoderm transition by regulating the expression of GCMB gene?

PS

You might find this posting reminiscent of, e.g., “TLR3“, one of my previous postings.

Addendum primum:

For a schematic figure of post-transcriptional control, see, e.g., here.

Addendum secundum:

08/19/11

I have fixed the link pointing to ExPASy.

Advertisements