Metaplasia is thought to arise from genetic reprogramming of stem cells (for details, see, e.g., 5th ed. of this book, p49.), and the essence of iPS cell method consists in such reprogramming. However, tadpole tail regeneration is not metaplastic. So I wish to raise the following question:
Will Xenopus/Wnt research turn out to be more fruitful than iPS cell research?
Wnt’s role in regeneration research cannot be ignored.
Wnt research is as fascinating as ever.
Again, Wnt research is as fascinating as ever.
Metaplasia is worth mentioning.