This posting is related to “NMDA receptor“, one of my previous postings.

This paper proposed two possible models of rat NR1/NR2A tetrameric complex, which leads me to raise the following two questions:

1. Can we assume that full-length human NR1 and NR2A form NR1-NR1-NR2A-NR2A complex as proposed in the above paper?

2. Can we observe the gating of full-length human NR1/NR2A complex using AFM in solution?